Lyrica Annouces Results of How It Works in the Brains of Patients with Fibromyalgia

Written by eHealth Navigator

Pfizer Inc. (NYSE: PFE) announced today the results of studies on Lyrica® (pregabalin) capsules CV presented at the American Pain Society Annual Meeting in Honolulu. The studies included exploratory research designed to provide new insight into how Lyrica works in the brains of patients with fibromyalgia. A total of seven Lyrica abstracts were presented.

It has been hypothesized that the central nervous system (CNS) in patients with fibromyalgia is hyper-sensitive to pain signals. These are the first exploratory data using fMRI and Lyrica that suggests an association between treatment and changes in central pain processing pathways in FM patients.

“This is the first exploratory fMRI study to investigate the mechanism of action of Lyrica in humans with fibromyalgia,” said study investigator Richard E. Harris, Ph.D., Assistant Professor, Department of Anesthesiology and Research Assistant Professor, Department of Internal Medicine, University of Michigan.

“This exploratory study not only shows how fibromyalgia affects the brain, it provides further insights on how Lyrica may impact central pain processing pathways in the brain.” “These data demonstrate Pfizer’s commitment to enhancing the scientific community’s understanding of Lyrica,” said Steven J. Romano, M.D., senior vice president, Head, Medicines Development Group, Global Primary Care Business Unit, Pfizer, Inc. “By using technologies such as fMRI, we can contribute to a growing body of research in pain physiology with the goal of answering patient needs in a more meaningful way.”

Last Updated on Friday, 14 June 2013 1:56PM